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Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data

Motivation: Haplotypes, defined as the sequence of alleles on one chromosome, are crucial for many genetic analyses. As experimental determination of haplotypes is extremely expensive, haplotypes are traditionally inferred using computational approaches from genotype data, i.e. the mixture of the ge...

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Hlavní autoři: Yang, Wen-Yun, Hormozdiari, Farhad, Wang, Zhanyong, He, Dan, Pasaniuc, Bogdan, Eskin, Eleazar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753566/
https://ncbi.nlm.nih.gov/pubmed/23825370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt386
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