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Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data

Motivation: Haplotypes, defined as the sequence of alleles on one chromosome, are crucial for many genetic analyses. As experimental determination of haplotypes is extremely expensive, haplotypes are traditionally inferred using computational approaches from genotype data, i.e. the mixture of the ge...

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Autori principali: Yang, Wen-Yun, Hormozdiari, Farhad, Wang, Zhanyong, He, Dan, Pasaniuc, Bogdan, Eskin, Eleazar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753566/
https://ncbi.nlm.nih.gov/pubmed/23825370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt386
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