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Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data

Motivation: Haplotypes, defined as the sequence of alleles on one chromosome, are crucial for many genetic analyses. As experimental determination of haplotypes is extremely expensive, haplotypes are traditionally inferred using computational approaches from genotype data, i.e. the mixture of the ge...

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Detalhes bibliográficos
Main Authors: Yang, Wen-Yun, Hormozdiari, Farhad, Wang, Zhanyong, He, Dan, Pasaniuc, Bogdan, Eskin, Eleazar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753566/
https://ncbi.nlm.nih.gov/pubmed/23825370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt386
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