Ex-Vivo Dynamic 3-D Culture of Human Tissues in the RCCS™ Bioreactor Allows the Study of Multiple Myeloma Biology and Response to Therapy

Three-dimensional (3-D) culture models are emerging as invaluable tools in tumor biology, since they reproduce tissue-specific structural features and cell-cell interactions more accurately than conventional 2-D cultures. Multiple Myeloma, which depends on myeloma cell-Bone Marrow microenvironment i...

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Main Authors: Ferrarini, Marina, Steimberg, Nathalie, Ponzoni, Maurilio, Belloni, Daniela, Berenzi, Angiola, Girlanda, Stefania, Caligaris-Cappio, Federico, Mazzoleni, Giovanna, Ferrero, Elisabetta
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753321/
https://ncbi.nlm.nih.gov/pubmed/23990965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071613
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