RCCS Bioreactor-Based Modelled Microgravity Induces Significant Changes on In Vitro 3D Neuroglial Cell Cultures

We propose a human-derived neuro-/glial cell three-dimensional in vitro model to investigate the effects of microgravity on cell-cell interactions. A rotary cell-culture system (RCCS) bioreactor was used to generate a modelled microgravity environment, and morphofunctional features of glial-like GL1...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Morabito, Caterina, Steimberg, Nathalie, Mazzoleni, Giovanna, Guarnieri, Simone, Fanò-Illic, Giorgio, Mariggiò, Maria A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309310/
https://ncbi.nlm.nih.gov/pubmed/25654124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/754283
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