Resveratrol Stimulates Sphingosine-1-Phosphate Signaling of Cathelicidin Production

We recently discovered a regulatory mechanism that stimulates production of the multifunctional antimicrobial peptide, cathelicidin antimicrobial peptide (CAMP). In response to subtoxic levels of ER stress, increased sphingosine-1-phosphate (S1P) production activates an NFκB→C/EBPα dependent pathway...

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Main Authors: Park, Kyungho, Elias, Peter M., Hupe, Melanie, Borkowski, Andrew W., Gallo, Richard L., Shin, Kyong-Oh, Lee, Yong-Moon, Holleran, Walter M., Uchida, Yoshikazu
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753186/
https://ncbi.nlm.nih.gov/pubmed/23856934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.133
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