A Novel Role of a Lipid Species, Sphingosine-1-Phosphate, in Epithelial Innate Immunity

A variety of external perturbations can induce endoplasmic reticulum (ER) stress, followed by stimulation of epithelial cells to produce an innate immune element, the cathelicidin antimicrobial peptide (CAMP). ER stress also increases production of the proapoptotic lipid ceramide and its antiapoptot...

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Detalhes bibliográficos
Main Authors: Park, Kyungho, Elias, Peter M., Shin, Kyoung-Oh, Lee, Yong-Moon, Hupe, Melanie, Borkowski, Andrew W., Gallo, Richard L., Saba, Julie, Holleran, Walter M., Uchida, Yoshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571353/
https://ncbi.nlm.nih.gov/pubmed/23230267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01103-12
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