A Novel Role of a Lipid Species, Sphingosine-1-Phosphate, in Epithelial Innate Immunity

A variety of external perturbations can induce endoplasmic reticulum (ER) stress, followed by stimulation of epithelial cells to produce an innate immune element, the cathelicidin antimicrobial peptide (CAMP). ER stress also increases production of the proapoptotic lipid ceramide and its antiapoptot...

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Autores principales: Park, Kyungho, Elias, Peter M., Shin, Kyoung-Oh, Lee, Yong-Moon, Hupe, Melanie, Borkowski, Andrew W., Gallo, Richard L., Saba, Julie, Holleran, Walter M., Uchida, Yoshikazu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571353/
https://ncbi.nlm.nih.gov/pubmed/23230267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01103-12
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