A Novel Role of a Lipid Species, Sphingosine-1-Phosphate, in Epithelial Innate Immunity

A variety of external perturbations can induce endoplasmic reticulum (ER) stress, followed by stimulation of epithelial cells to produce an innate immune element, the cathelicidin antimicrobial peptide (CAMP). ER stress also increases production of the proapoptotic lipid ceramide and its antiapoptot...

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Главные авторы: Park, Kyungho, Elias, Peter M., Shin, Kyoung-Oh, Lee, Yong-Moon, Hupe, Melanie, Borkowski, Andrew W., Gallo, Richard L., Saba, Julie, Holleran, Walter M., Uchida, Yoshikazu
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571353/
https://ncbi.nlm.nih.gov/pubmed/23230267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01103-12
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