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Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidates

We evaluated B memory responses in healthy adult volunteers who received one oral dose of live-attenuated Shigella flexneri 2a vaccine. LPS-specific B(M) cells increased from a median of 0 at baseline to 20 spot forming cells (SFC)/10(6) expanded cells following vaccination (p = 0.008). A strong cor...

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Détails bibliographiques
Auteurs principaux: Simon, J.K., Wahid, R., Maciel, M., Picking, W.L., Kotloff, K.L., Levine, M.M., Sztein, M.B.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753173/
https://ncbi.nlm.nih.gov/pubmed/19022324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.10.081
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