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TLR9-Targeted Biodegradable Nanoparticles as Immunization Vectors Protect against West Nile Encephalitis

Vaccines that activate humoral and cell-mediated immune responses are urgently needed for many infectious agents, including the flaviviruses dengue and West Nile (WN) virus. Vaccine development would be greatly facilitated by a new approach, in which nanoscale modules (Ag, adjuvant, and carrier) are...

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Detalhes bibliográficos
Main Authors: Demento, Stacey L., Bonafé, Nathalie, Cui, Weiguo, Kaech, Susan M., Caplan, Michael J., Fikrig, Erol, Ledizet, Michel, Fahmy, Tarek M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753007/
https://ncbi.nlm.nih.gov/pubmed/20660705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000768
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