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Very High Density of CHO Cells in Perfusion by ATF or TFF in WAVE Bioreactor™. Part I. Effect of the Cell Density on the Process

High cell density perfusion process of antibody producing CHO cells was developed in disposable WAVE Bioreactor™ using external hollow fiber filter as cell separation device. Both “classical” tangential flow filtration (TFF) and alternating tangential flow system (ATF) equipment were used and compar...

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Bibliografske podrobnosti
Main Authors: Clincke, Marie-Françoise, Mölleryd, Carin, Zhang, Ye, Lindskog, Eva, Walsh, Kieron, Chotteau, Véronique
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752962/
https://ncbi.nlm.nih.gov/pubmed/23436789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.1704
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