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Optimization of the medium perfusion rate in a packed-bed bioreactor charged with CHO cells
In the present study, the optimal medium perfusion rate to be used for the continuous culture of a recombinant CHO cell line in a packed-bed bioreactor made of Fibra-Cel(®) disk carriers was determined. A first-generation process had originally been designed with a high perfusion rate, in order to r...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Kluwer Academic Publishers
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449470/ https://ncbi.nlm.nih.gov/pubmed/19003257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-005-2105-z |
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