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Cdc42 Deficiency Causes Ciliary Abnormalities and Cystic Kidneys
Ciliogenesis and cystogenesis require the exocyst, a conserved eight-protein trafficking complex that traffics ciliary proteins. In culture, the small GTPase Cdc42 co-localizes with the exocyst at primary cilia and interacts with the exocyst component Sec10. The role of Cdc42 in vivo, however, is no...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752951/ https://ncbi.nlm.nih.gov/pubmed/23766535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012121236 |
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