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The Small GTPase Cdc42 Is Necessary for Primary Ciliogenesis in Renal Tubular Epithelial Cells

Primary cilia are found on many epithelial cell types, including renal tubular epithelial cells, where they participate in flow sensing. Disruption of cilia function has been linked to the pathogenesis of polycystic kidney disease. We demonstrated previously that the exocyst, a highly conserved eigh...

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Bibliografski detalji
Glavni autori: Zuo, Xiaofeng, Fogelgren, Ben, Lipschutz, Joshua H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121392/
https://ncbi.nlm.nih.gov/pubmed/21543338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238469
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