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The Small GTPase Cdc42 Is Necessary for Primary Ciliogenesis in Renal Tubular Epithelial Cells

Primary cilia are found on many epithelial cell types, including renal tubular epithelial cells, where they participate in flow sensing. Disruption of cilia function has been linked to the pathogenesis of polycystic kidney disease. We demonstrated previously that the exocyst, a highly conserved eigh...

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Detalhes bibliográficos
Main Authors: Zuo, Xiaofeng, Fogelgren, Ben, Lipschutz, Joshua H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121392/
https://ncbi.nlm.nih.gov/pubmed/21543338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238469
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