Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence and mortality in elderly individuals: the Normative Aging Study

BACKGROUND: Global genomic hypomethylation is a common epigenetic event in cancer that mostly results from hypomethylation of repetitive DNA elements. Case-control studies have associated blood leukocyte DNA hypomethylation with several cancers. Because samples in case-control studies are collected...

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Autori principali: Zhu, Zhong-Zheng, Sparrow, David, Hou, Lifang, Tarantini, Letizia, Bollati, Valentina, Litonjua, Augusto A., Zanobetti, Antonella, Vokonas, Pantel, Wright, Robert O., Baccarelli, Andrea, Schwartz, Joel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752839/
https://ncbi.nlm.nih.gov/pubmed/21188491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-010-9715-2
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