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Decline in Genomic DNA Methylation through Aging in a Cohort of Elderly Subjects

Loss of genomic DNA methylation has been found in a variety of common human age-related diseases. Whether DNA methylation decreases over time as individuals age is unresolved. We measured DNA methylation in 1,097 blood DNA samples from 718 elderly subjects between 55–92 years of age (1–3 samples/sub...

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Main Authors: Bollati, Valentina, Schwartz, Joel, Wright, Robert, Litonjua, Augusto, Tarantini, Letizia, Suh, Helen, Sparrow, David, Vokonas, Pantel, Baccarelli, Andrea
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956267/
https://ncbi.nlm.nih.gov/pubmed/19150625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.12.003
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