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Decline in Genomic DNA Methylation through Aging in a Cohort of Elderly Subjects

Loss of genomic DNA methylation has been found in a variety of common human age-related diseases. Whether DNA methylation decreases over time as individuals age is unresolved. We measured DNA methylation in 1,097 blood DNA samples from 718 elderly subjects between 55–92 years of age (1–3 samples/sub...

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Detalhes bibliográficos
Main Authors: Bollati, Valentina, Schwartz, Joel, Wright, Robert, Litonjua, Augusto, Tarantini, Letizia, Suh, Helen, Sparrow, David, Vokonas, Pantel, Baccarelli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956267/
https://ncbi.nlm.nih.gov/pubmed/19150625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.12.003
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