Optimization and Validation of a Plaque Reduction Neutralization Test for the Detection of Neutralizing Antibodies to Four Serotypes of Dengue Virus Used in Support of Dengue Vaccine Development

A dengue plaque reduction neutralization test (PRNT) to measure dengue serotype–specific neutralizing antibodies for all four virus serotypes was developed, optimized, and validated in accordance with guidelines for validation of bioanalytical test methods using human serum samples from dengue-infec...

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Hlavní autoři: Timiryasova, Tatyana M., Bonaparte, Matthew I., Luo, Ping, Zedar, Rebecca, Hu, Branda T., Hildreth, Stephen W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Tropical Medicine and Hygiene 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752766/
https://ncbi.nlm.nih.gov/pubmed/23458954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.12-0461
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