Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production

The lungs of cystic fibrosis (CF) patients are commonly colonized with Pseudomonas aeruginosa biofilms. Chronic endobronchial P. aeruginosa infections are impossible to eradicate with antibiotics, but intensive suppressive antibiotic therapy is essential to maintain the lung function of CF patients....

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Main Authors: Bagge, Niels, Schuster, Martin, Hentzer, Morten, Ciofu, Oana, Givskov, Michael, Greenberg, Everett Peter, Høiby, Niels
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Mechanisms of Action: Physiological Effects
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC375275/
https://ncbi.nlm.nih.gov/pubmed/15047518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1175-1187.2004
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