Interplay between the overlapping ends of tropomyosin and the N terminus of cardiac troponin T affects tropomyosin states on actin

The functional significance of the molecular swivel at the head-to-tail overlapping ends of contiguous tropomyosin (Tm) dimers in striated muscle is unknown. Contractile measurements were made in muscle fibers from transgenic (TG) mouse hearts that expressed a mutant α-Tm (Tm(H276N)). We also recons...

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Bibliografiske detaljer
Main Authors: Mamidi, Ranganath, Michael, John Jeshurun, Muthuchamy, Mariappan, Chandra, Murali
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2013
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752546/
https://ncbi.nlm.nih.gov/pubmed/23748972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-232363
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