Changes in prion replication environment cause prion strain mutation

Interspecies prion transmission often leads to stable changes in physical and biological features of prion strains, a phenomenon referred to as a strain mutation. It remains unknown whether changes in the replication environment in the absence of changes in PrP primary structure can be a source of s...

Full description

Saved in:
Bibliographic Details
Main Authors: Gonzalez-Montalban, Nuria, Lee, Young Jin, Makarava, Natallia, Savtchenko, Regina, Baskakov, Ilia V.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2013
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752540/
https://ncbi.nlm.nih.gov/pubmed/23729586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-230466
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items