Cancer- and endotoxin-induced cachexia require intact glucocorticoid signaling in skeletal muscle

Cachexia is a wasting condition defined by skeletal muscle atrophy in the setting of systemic inflammation. To explore the site at which inflammatory mediators act to produce atrophy in vivo, we utilized mice with a conditional deletion of the inflammatory adaptor protein myeloid differentiation fac...

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Bibliographic Details
Main Authors: Braun, Theodore P., Grossberg, Aaron J., Krasnow, Stephanie M., Levasseur, Peter R., Szumowski, Marek, Zhu, Xin Xia, Maxson, Julia E., Knoll, J. Gabriel, Barnes, Anthony P., Marks, Daniel L.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2013
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752537/
https://ncbi.nlm.nih.gov/pubmed/23733748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-230375
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