Cancer- and endotoxin-induced cachexia require intact glucocorticoid signaling in skeletal muscle

Cachexia is a wasting condition defined by skeletal muscle atrophy in the setting of systemic inflammation. To explore the site at which inflammatory mediators act to produce atrophy in vivo, we utilized mice with a conditional deletion of the inflammatory adaptor protein myeloid differentiation fac...

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Detalhes bibliográficos
Main Authors: Braun, Theodore P., Grossberg, Aaron J., Krasnow, Stephanie M., Levasseur, Peter R., Szumowski, Marek, Zhu, Xin Xia, Maxson, Julia E., Knoll, J. Gabriel, Barnes, Anthony P., Marks, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752537/
https://ncbi.nlm.nih.gov/pubmed/23733748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-230375
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