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ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury
In kidneys, each tubular epithelial cell contains a primary cilium that protrudes from the apical surface. Ciliary dysfunction was recently linked to acute kidney injury (AKI) following renal ischemia-reperfusion. Whether ciliary regulation is a general pathogenic mechanism in AKI remains unclear. M...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752396/ https://ncbi.nlm.nih.gov/pubmed/23727409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.05.023 |
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