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ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury

In kidneys, each tubular epithelial cell contains a primary cilium that protrudes from the apical surface. Ciliary dysfunction was recently linked to acute kidney injury (AKI) following renal ischemia-reperfusion. Whether ciliary regulation is a general pathogenic mechanism in AKI remains unclear. M...

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Autors principals: Wang, Shixuan, Wei, Qingqing, Dong, Guie, Dong, Zheng
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752396/
https://ncbi.nlm.nih.gov/pubmed/23727409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.05.023
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