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A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

The absence of the fragile X mental retardation protein (FMRP), encoded by the FMR1 gene, is responsible for pathologic manifestations in the Fragile X Syndrome, the most frequent cause of inherited mental retardation. FMRP is an RNA-binding protein associated with polysomes as part of a messenger r...

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Библиографические подробности
Главные авторы: Schenck, Annette, Bardoni, Barbara, Moro, Annamaria, Bagni, Claudia, Mandel, Jean-Louis
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC37523/
https://ncbi.nlm.nih.gov/pubmed/11438699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151231598
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