Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex

Brefeldin A-inhibited guanine nucleotide-exchange factors BIG1 and BIG2 activate, through their Sec7 domains, ADP ribosylation factors (Arfs) by accelerating the replacement of Arf-bound GDP with GTP for initiation of vesicular transport or activation of specific enzymes that modify important phosph...

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Hlavní autoři: Le, Kang, Li, Chun-Chun, Ye, Guan, Moss, Joel, Vaughan, Martha
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752278/
https://ncbi.nlm.nih.gov/pubmed/23918382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312531110
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