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Heterogeneity in protein expression induces metabolic variability in a modeled Escherichia coli population
Stochastic gene expression can lead to phenotypic differences among cells even in isogenic populations growing under macroscopically identical conditions. Here, we apply flux balance analysis in investigating the effects of single-cell proteomics data on the metabolic behavior of an in silico Escher...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752265/ https://ncbi.nlm.nih.gov/pubmed/23908403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222569110 |
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