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Interferon regulatory factor 3 controls interleukin-17 expression in CD8 T lymphocytes
IFN regulatory factor (IRF) 3 plays a key role in innate responses against viruses. Herein we assessed its contribution to T-cell activation. We observed that poly(I:C)-induced IRF3 activation in CD8 T cells represses IL-17 expression in a type I IFN-independent fashion. Even in the absence of poly(...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752229/ https://ncbi.nlm.nih.gov/pubmed/23918362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219221110 |
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