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Experiments on the role of deleterious mutations as stepping stones in adaptive evolution

Many evolutionary studies assume that deleterious mutations necessarily impede adaptive evolution. However, a later mutation that is conditionally beneficial may interact with a deleterious predecessor before it is eliminated, thereby providing access to adaptations that might otherwise be inaccessi...

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Detalhes bibliográficos
Main Authors: Covert, Arthur W., Lenski, Richard E., Wilke, Claus O., Ofria, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752215/
https://ncbi.nlm.nih.gov/pubmed/23918358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313424110
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