載入...

MC1R and cAMP signaling inhibit cdc25B activity and delay cell cycle progression in melanoma cells

The melanocortin 1 receptor (MC1R) mediates the tanning response through induction of cAMP and downstream pigmentary enzymes. Diminished function alleles of MC1R are associated with decreased tanning and increased melanoma risk, which has been attributed to increased rates of mutation. We have found...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Lyons, Jesse, Bastian, Boris C., McCormick, Frank
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752210/
https://ncbi.nlm.nih.gov/pubmed/23908401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201917110
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!