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New combinations and immunotherapies for melanoma: latest evidence and clinical utility

Until recently there was no effective systemic therapy for metastatic melanoma. Increased understanding of tumor biology and immune regulation has led to the development of drugs targeting the mitogen-activated protein kinase (MAPK) pathway (BRAF inhibitors and MEK inhibitors) and T-cell regulation...

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Autors principals: Menzies, Alexander M., Long, Georgina V.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752177/
https://ncbi.nlm.nih.gov/pubmed/23997828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834013499637
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