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Novel cancer antigens for personalized immunotherapies: latest evidence and clinical potential

The clinical success of monoclonal antibody immune checkpoint modulators such as ipilimumab, which targets cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), and the recently approved agents nivolumab and pembrolizumab, which target programmed cell death receptor 1 (PD-1), has stimulated renewed...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Wurz, Gregory T., Kao, Chiao-Jung, DeGregorio, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699263/
https://ncbi.nlm.nih.gov/pubmed/26753003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834015615514
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