Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons

Glucagon-like peptides (GLP-1/2) are co-produced and highlighted as key modulators to improve glucose homeostasis and insulin sensitivity after bariatric surgery. However, it is unknown if CNS GLP-2 plays any physiological role in the control of glucose homeostasis and insulin sensitivity. We show t...

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Detalhes bibliográficos
Main Authors: Shi, Xuemei, Zhou, Fuguo, Li, Xiaojie, Chang, Benny, Li, Depei, Wang, Yi, Tong, Qingchun, Xu, Yong, Fukuda, Makoto, Zhao, Jean J., Li, Defa, Burrin, Douglas G., Chan, Lawrence, Guan, Xinfu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752162/
https://ncbi.nlm.nih.gov/pubmed/23823479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.06.014
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