Insulin Receptor Signaling in POMC, but Not AgRP, Neurons Controls Adipose Tissue Insulin Action

Insulin is a key regulator of adipose tissue lipolysis, and impaired adipose tissue insulin action results in unrestrained lipolysis and lipotoxicity, which are hallmarks of the metabolic syndrome and diabetes. Insulin regulates adipose tissue metabolism through direct effects on adipocytes and thro...

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Publicado en:Diabetes
Autores principales: Shin, Andrew C., Filatova, Nika, Lindtner, Claudia, Chi, Tiffany, Degann, Seta, Oberlin, Douglas, Buettner, Christoph
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2017
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440019/
https://ncbi.nlm.nih.gov/pubmed/28385803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-1238
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