Autism-Associated Mutations in ProSAP2/Shank3 Impair Synaptic Transmission and Neurexin–Neuroligin-Mediated Transsynaptic Signaling

Mutations in several postsynaptic proteins have recently been implicated in the molecular pathogenesis of autism and autism spectrum disorders (ASDs), including Neuroligins, Neurexins, and members of the ProSAP/Shank family, thereby suggesting that these genetic forms of autism may share common syna...

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Detalhes bibliográficos
Main Authors: Arons, Magali H., Thynne, Charlotte J., Grabrucker, Andreas M., Li, Dong, Schoen, Michael, Cheyne, Juliette E., Boeckers, Tobias M., Montgomery, Johanna M., Garner, Craig C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752148/
https://ncbi.nlm.nih.gov/pubmed/23100419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2215-12.2012
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