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Opioids Disrupt Pro-Nociceptive Modulation Mediated by Raphe Magnus

In anesthetized rats, opioid analgesia is accompanied by a specific pattern of tonic activity in two neuronal populations within the medullary raphe magnus (RM): opioids silence pain-facilitatory ON cells and produce sustained discharge in pain-inhibitory OFF cells. These tonic activity patterns, hy...

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Hlavní autoři: Hellman, Kevin M., Mason, Peggy
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752126/
https://ncbi.nlm.nih.gov/pubmed/23035079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1551-12.2012
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