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Opioids Disrupt Pro-Nociceptive Modulation Mediated by Raphe Magnus
In anesthetized rats, opioid analgesia is accompanied by a specific pattern of tonic activity in two neuronal populations within the medullary raphe magnus (RM): opioids silence pain-facilitatory ON cells and produce sustained discharge in pain-inhibitory OFF cells. These tonic activity patterns, hy...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752126/ https://ncbi.nlm.nih.gov/pubmed/23035079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1551-12.2012 |
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