A Unilateral Negative Feedback Loop Between miR-200 microRNAs and Sox2/E2F3 Controls Neural Progenitor Cell-Cycle Exit and Differentiation

MicroRNAs have emerged as key posttranscriptional regulators of gene expression during vertebrate development. We show that the miR-200 family plays a crucial role for the proper generation and survival of ventral neuronal populations in the murine midbrain/hindbrain region, including midbrain dopam...

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Detalhes bibliográficos
Main Authors: Peng, Changgeng, Li, Na, Ng, Yen-Kar, Zhang, Jingzhong, Meier, Florian, Theis, Fabian J., Merkenschlager, Matthias, Chen, Wei, Wurst, Wolfgang, Prakash, Nilima
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752087/
https://ncbi.nlm.nih.gov/pubmed/22993445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2124-12.2012
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