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Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system
How a pool of undifferentiated neural progenitor cells is maintained in the developing nervous system is an issue that remains unresolved. One of the key transcription factors for self-renewal of these cells is Sox2, the forced expression of which has been shown to inhibit neuronal differentiation i...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932859/ https://ncbi.nlm.nih.gov/pubmed/24501124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308758111 |
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