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Benchmark dose analysis via nonparametric regression modeling
Estimation of benchmark doses (BMDs) in quantitative risk assessment traditionally is based upon parametric dose-response modeling. It is a well-known concern, however, that if the chosen parametric model is uncertain and/or misspecified, inaccurate and possibly unsafe low-dose inferences can result...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752015/ https://ncbi.nlm.nih.gov/pubmed/23683057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/risa.12066 |
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