The Impact of Model Uncertainty on Benchmark Dose Estimation

We study the popular benchmark dose (BMD) approach for estimation of low exposure levels in toxicological risk assessment, focusing on dose-response experiments with quantal data. In such settings, representations of the risk are traditionally based on a specified, parametric, dose-response model. I...

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Main Authors: West, R. Webster, Piegorsch, Walter W., Peña, Edsel A., An, Lingling, Wu, Wensong, Wickens, Alissa A., Xiong, Hui, Chen, Wenhai
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686319/
https://ncbi.nlm.nih.gov/pubmed/23794799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/env.2180
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