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Allosteric modulation of alpha4beta2 nicotinic acetylcholine receptors by HEPES()
A number of new positive allosteric modulators (PAMs) have been reported that enhance responses of neuronal alpha7 and alpha4beta2 nicotinic acetylcholine receptor subtypes to orthosteric ligands. PAMs represent promising new leads for the development of therapeutic agents for disorders involving al...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752001/ https://ncbi.nlm.nih.gov/pubmed/22732654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.06.001 |
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