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Cell Envelope Protein PPE68 Contributes to Mycobacterium tuberculosis RD1 Immunogenicity Independently of a 10-Kilodalton Culture Filtrate Protein and ESAT-6

The protective efficacy of Mycobacterium bovis BCG can be markedly augmented by stable integration of Mycobacterium tuberculosis genomic region RD1. BCG complemented with RD1 (BCG::RD1) encodes nine additional proteins. Among them, 10-kDa culture filtrate protein (CFP-10) and ESAT-6 (6-kDa early sec...

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Bibliografiske detaljer
Main Authors: Demangel, Caroline, Brodin, Priscille, Cockle, Paul J., Brosch, Roland, Majlessi, Laleh, Leclerc, Claude, Cole, Stewart T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC375197/
https://ncbi.nlm.nih.gov/pubmed/15039340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.4.2170-2176.2004
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