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Rapid estimation of hydration thermodynamics of macromolecular regions

This work describes a novel protocol to efficiently calculate the local free energy of hydration of specific regions in macromolecules. The method employs Monte Carlo simulations in the grand canonical ensemble to generate water configurations in a selected spherical region in the macromolecule. Exc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Raman, E. Prabhu, MacKerell, Alexander D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AIP Publishing LLC 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751957/
https://ncbi.nlm.nih.gov/pubmed/23927290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4817344
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