Knockdown of Human TCF4 Affects Multiple Signaling Pathways Involved in Cell Survival, Epithelial to Mesenchymal Transition and Neuronal Differentiation

Haploinsufficiency of TCF4 causes Pitt-Hopkins syndrome (PTHS): a severe form of mental retardation with phenotypic similarities to Angelman, Mowat-Wilson and Rett syndromes. Genome-wide association studies have also found that common variants in TCF4 are associated with an increased risk of schizop...

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Bibliografiske detaljer
Main Authors: Forrest, Marc P., Waite, Adrian J., Martin-Rendon, Enca, Blake, Derek J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751932/
https://ncbi.nlm.nih.gov/pubmed/24058414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073169
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