Barnacle: detecting and characterizing tandem duplications and fusions in transcriptome assemblies

BACKGROUND: Chimeric transcripts, including partial and internal tandem duplications (PTDs, ITDs) and gene fusions, are important in the detection, prognosis, and treatment of human cancers. RESULTS: We describe Barnacle, a production-grade analysis tool that detects such chimeras in de novo assembl...

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Библиографические подробности
Главные авторы: Swanson, Lucas, Robertson, Gordon, Mungall, Karen L, Butterfield, Yaron S, Chiu, Readman, Corbett, Richard D, Docking, T Roderick, Hogge, Donna, Jackman, Shaun D, Moore, Richard A, Mungall, Andrew J, Nip, Ka Ming, Parker, Jeremy DK, Qian, Jenny Qing, Raymond, Anthony, Sung, Sandy, Tam, Angela, Thiessen, Nina, Varhol, Richard, Wang, Sherry, Yorukoglu, Deniz, Zhao, YongJun, Hoodless, Pamela A, Sahinalp, S Cenk, Karsan, Aly, Birol, Inanc
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Methodology Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751903/
https://ncbi.nlm.nih.gov/pubmed/23941359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-550
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