Heterologous Reconstitution of the Intact Geodin Gene Cluster in Aspergillus nidulans through a Simple and Versatile PCR Based Approach

Fungal natural products are a rich resource for bioactive molecules. To fully exploit this potential it is necessary to link genes to metabolites. Genetic information for numerous putative biosynthetic pathways has become available in recent years through genome sequencing. However, the lack of soli...

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Autores principales: Nielsen, Morten Thrane, Nielsen, Jakob Blæsbjerg, Anyaogu, Dianna Chinyere, Holm, Dorte Koefoed, Nielsen, Kristian Fog, Larsen, Thomas Ostenfeld, Mortensen, Uffe Hasbro
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751827/
https://ncbi.nlm.nih.gov/pubmed/24009710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072871
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