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An apoptosis-independent role of SMAC in tumor suppression

Reduced expression of the pro-apoptotic protein SMAC (second mitochondria-derived activator of caspase) has been reported to correlate with cancer progression, while its significance and underlying mechanisms are poorly understood. In this study, we investigated the role of SMAC in intestinal tumori...

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Autori principali: Qiu, W, Liu, H, Sebastini, A, Sun, Q, Wang, H, Zhang, L, Yu, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751796/
https://ncbi.nlm.nih.gov/pubmed/22751125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.265
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