Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members

BACKGROUND: Polyunsaturated fatty acids (PUFAs) have positive effect on the regulation of plasma lipids. But the mechanism for them to modulate lipid homeostasis in macrophage is still unclear. In this study, we employed PUFA to pretreat macrophages and evaluated the variations of lipid droplet (LD)...

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Hlavní autoři: Song, Yue, Zhang, Li-Jun, Li, Hang, Gu, Yu, Li, Fan-Fan, Jiang, Li-Na, Liu, Fang, Ye, Jing, Li, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751560/
https://ncbi.nlm.nih.gov/pubmed/23879935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-111
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