Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members

BACKGROUND: Polyunsaturated fatty acids (PUFAs) have positive effect on the regulation of plasma lipids. But the mechanism for them to modulate lipid homeostasis in macrophage is still unclear. In this study, we employed PUFA to pretreat macrophages and evaluated the variations of lipid droplet (LD)...

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Detalhes bibliográficos
Main Authors: Song, Yue, Zhang, Li-Jun, Li, Hang, Gu, Yu, Li, Fan-Fan, Jiang, Li-Na, Liu, Fang, Ye, Jing, Li, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751560/
https://ncbi.nlm.nih.gov/pubmed/23879935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-111
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