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Synthesis and Evaluation of Methylated Arylazepine Compounds for PET Imaging of 5-HT(2c) Receptors

[Image: see text] The serotonin 5-HT(2c) receptor is implicated in a number of diseases including obesity, depression, anxiety, and schizophrenia. In order to ascribe the role of 5-HT(2c) in these diseases, a method for measuring 5-HT(2c )density and function in vivo, such as with positron emission...

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Autors principals: Granda, Michael L., Carlin, Stephen M., Moseley, Christian K., Neelamegam, Ramesh, Mandeville, Joseph B., Hooker, Jacob M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2012
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751540/
https://ncbi.nlm.nih.gov/pubmed/23421677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300223d
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