Absence of Interleukin-4 Determines Less Severe Pulmonary Paracoccidioidomycosis Associated with Impaired Th2 Response

Host resistance to paracoccidiodomycosis, the main deep mycosis in Latin America, is mainly due to cellular immunity and gamma interferon (IFN-γ) production. To assess the role of interleukin-4 (IL-4), a Th2-inducing cytokine, pulmonary paracoccidioidomycosis was studied in IL-4-deficient (IL-4(−/−)...

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Detaylı Bibliyografya
Asıl Yazarlar: Pina, Adriana, Valente-Ferreira, Rita C., Molinari-Madlum, Eugênia E. W., Vaz, Celidéia A. C., Keller, Alexandre C., Calich, Vera L. G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2004
Konular:
Fungal and Parasitic Infections
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC375147/
https://ncbi.nlm.nih.gov/pubmed/15039362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.4.2369-2378.2004
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